1951

• Atomic bomb scare hits area

1952

• Piketon selected as a site for uranium enrichment plant

1953

• OSCO begins making iron castings

• Clay Township voters rejected proposal to incorporate Rosemount
• Happy Hearts opened
• Portsmouth High School has undefeated season

1956

• Uranium Enrichment plant construction completed

1957

• Selby Shoe Company closed and liquidated
• Greater Portsmouth Regional Airport opens
• Three-alarm fire takes out some businesses on Gallia Street in the center of Portsmouth
• Flu-like symptoms closed several Scioto County schools

1958

• Steam engines make last run

1959

• Roy Rogers Festival began at the Scioto County Fair

1960

• City Council purchased Massie School from city school district (later named Griffin Hall)