1941

• Fire destroys Minford High School

• Fire destroys South Webster High School

• United States enters WWII

• Columbia Theatre opened

1942

• First YMCA building to offer community facilities

• Rationing begins in Scioto County

• WWII draft begin in Scioto County

• Movie star Marlene Dietrich visited Portsmouth to promote the sale of war bonds

1945

• Schirrmann Hospital reopened as Smith-Everett Hospital

• Branch Rickey signs 1st black player; Jackie Robinson to Major League Ball

• Japan surrenders, WWII ends

• Portsmouth avoid another flood, crested at 64.9 feet

1947

• Philadelphia Athletics professional team began hosting games at Riverside Park

1948

• Vern Riffe Sr., takes office as New Boston mayor

1949

• Scioto Breeze Drive-In theater was built

1950

• Henry Oberling Motor Company officially came into existence

• Portsmouth Athletics professional team left Portsmouth

• Blizzard claims three lives

• Phone strike causes 61 days of no service

• South Webster builds new high school