1922

• Hopedale Home established on Milldale Road in New Boston

• Ohio Division of Conservation and natural Resources purchased about 5,000 acres for the beginning of what is now known as Shawnee State Forest

• Ohio National Guard purchase the Windel building located on Third Street between Washington and Court Streets

1923

• Pastime Theater (South Webster) offers silent movies

• Hurth Hotel, owned by Adolph Hurth, was built at Third and Chillicothe

1924

• Mercy Hospital opened

1925

• Hempstead Hospital opened

• Masonic Temple destroyed by fire, damages estimated at $1 million.

1926

• Semi-pro football clubs Portsmouth Presidents and the Portsmouth Merchants established

1927

• Building of Scioto County Courthouse completed

• U.S. Grant Bridge opened to foot traffic

• J.C. Penney opened on Chillicothe Street

• Semi-pro football club Portsmouth Shoe-Steels

1928

• Portsmouth City Council passed legislation to place an $80,000 bond issue on the upcoming election to build a stadium on the banks of the Ohio River

• City Charter passed for the City of Portsmouth

• Jim Thorpe became the coach of the first professional football team (Portsmouth Shoe-Steels)

• Portsmouth Spartans became an NFL club

1929

• Spartans played their first National Football League losing to the Green Bay Packers 14-0

• Union Street School was leveled by fire

• Portsmouth reservoir is built

1930

• Universal Stadium completed in time to host the first game of the Portsmouth Spartans as a member of the National Football League

• Portsmouth Spartans defeated the Green Bay Packers 13-6

• Four new high schools were constructed:  Scudder, Grant, Roosevelt, Harding (Sciotoville)

• First wrestling match at Baesman's Arena